Cell Surface Receptors by K. Christopher Garcia (Eds.)

By K. Christopher Garcia (Eds.)

Phone floor Receptors includes an intensive dialogue of phone floor receptors in eleven chapters via specialists of their box. As mobile floor receptors are excited about virtually each element of signaling in the course of the physique, the subject has been of excessive curiosity locally lately. chosen Contents:-Structures of Axon assistance Molecules and Their Neuronal Receptors-Shared Cytokine Signaling Receptor-NKG2D and similar Immunoreceptors-Inonotropic Glutamat Receptor attractiveness and Activation-Chemotaxis Receptors and Signaling

Show description

Read or Download Cell Surface Receptors PDF

Best cell biology books

Peptide Growth Factors Part B

The seriously acclaimed laboratory average, tools in Enzymology , is among the such a lot hugely revered courses within the box of biochemistry. considering 1955, each one quantity has been eagerly awaited, often consulted, and praised via researchers and reviewers alike. The sequence includes a lot fabric nonetheless suitable this day - actually a vital book for researchers in all fields of existence sciences.

Liposomes, Part D

Liposomes are mobile buildings made from lipid molecules. very important as a mobile version within the research of easy biology, liposomes also are utilized in medical functions reminiscent of drug supply and virus stories. Liposomes half D is a continuation of earlier MIE Liposome volumes A, B, and C. Contents: Antibody or Ligand distinctive Liposomes; surroundings delicate liposomes; liposomal oligonucleotides; liposomes in vivo

Isolation of Plant Organelles and Structures: Methods and Protocols

This e-book brings jointly the foremost options utilized in the isolation or enrichment of person populations of organelles and different subcellular constructions from vegetation with the target that, via having the ability to isolate subcellular constructions, the study and figuring out of varied aspects of compartmentalized functionality in plant cells should be complicated.

Additional resources for Cell Surface Receptors

Example text

30 31 31 32 33 33 35 37 37 41 42 43 44 47 47 51 51 53 54 56 57 Abstract Integrins are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis.

2002). Two recent mutational studies provide direct evidence that downward movement of the 7-helix of the I-like domain activates ligand binding. Mutagenic introduction of a disulfide bond between the I-like 6-strand and 7-helix designed to stabilize the 7-helix in the conformation seen in the bent crystal structure abolished the ability to activate ligand binding by integrin IIb 3. , 2004b). In another study, the effect of 7-helix displacement on the 6- 7 loop was mimicked by shortening the 7-helix by 4 residue deletions of $1 turn of 7-helix.

The bipolar sites thus stabilize two alternative phases of adhesion. The higher affinity of Ca2þ than Mg2þ at the LIMBS is explained by the presence of three carbonyl O coordinations, for which Ca2þ has greater propensity than Mg2þ (Fig. 7A). The activating effect of Mn2þ and inhibitory effect of Ca2þ at the ADMIDAS may similarly be explained by the propensity of Ca2þ but not Mn2þ to form a carbonyl O coordination to the backbone of the 6- 7 loop (Fig. 7B). This carbonyl coordination to Ca2þ seen in closed structures with Ca2þ (Fig.

Download PDF sample

Rated 4.20 of 5 – based on 47 votes