Cell adhesion and communication mediated by the CEA family : by Clifford P Stanners

By Clifford P Stanners

Considers the hot explosion of data in regards to the carcinoembryonic antigen (CEA) family members, which resulted from the molecular cloning of loved one genes in 1986.
Results indicating CEA relations upregulated in melanoma can have an instrumental function in malignant transformation and metastasis, whereas those who are downregulated can have tumor suppressive services are thought of. stories, fresh effects, hypotheses, and scientific purposes concerning a gene relations that, from its common adjustments in expression in tumors at many websites, may be considered as a "major participant" in human melanoma also are mentioned. the conventional features reminiscent of epithelial and hematopoietic adhesion and signalling molecules are explored, and the doubtless particular position of this kin in evolution is brought.
This quantity might be of curiosity to researchers within the fields of intercellular adhesion, evolution, and molecular attractiveness, in addition to clinicians drawn to the new wisdom relating to a tumor marker regularly utilised within the health facility, and firms wishing to take advantage of this cancer-related relations for novel advertisement purposes within the biomedical sphere.

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