Carrier-Based Drug Delivery by Sönke Svenson

By Sönke Svenson

Carrier established Drug Delivery is split into 3 major sections that hide significant provider platforms used to carry medicinal drugs in addition to DNA. the 1st part describes using liposomes and tubules as service platforms. The 8 chapters during this part record using stimuli-responsive liposomes and liposome-polymer complexes in drug and DNA supply, the applying of impartial liposomes in gene move, and using niosomes within the supply of poorly soluble medicines. The position of vesicle form in supply is mentioned, by way of studies at the use of microtubules and templated nanotubes for the supply and separation of bioactives.

The moment part is dedicated to using polymeric micelles as targetable pharmaceutical vendors, novel therapeutics in drug supply, and endosomolytic brokers for gene supply. The part concludes with a bankruptcy at the use of ultrasound to enhance the potency of polymeric micelles as vendors.

The 3rd part offers 9 chapters at the use of micro- and nanoparticulate providers in drug supply. those chapters handle how to organize certain micro- and nanoparticles, the usage of lipids in peptide and protein unencumber, and the development of nanocontainers, both by way of stabilization of liposomal templates or by means of layer-by-layer deposition of polymers round colloidal templates. The aid or prevention of burst free up from matrices is mentioned, in addition to using mucoadhesion and mechanical adhesion for localized nasal and peroral supply of actives.

Show description

Read or Download Carrier-Based Drug Delivery PDF

Similar pharmacology books

Toxicological profiles - Chlorfenvinphos

This booklet was once digitized and reprinted from the collections of the college of California Libraries. It used to be made from electronic photographs created during the libraries’ mass digitization efforts. The electronic pictures have been wiped clean and ready for printing via automatic methods. regardless of the cleansing technique, occasional flaws should still be current that have been a part of the unique paintings itself, or brought in the course of digitization.

Proteins and Peptides: Pharmacokinetic, Pharmacodynamic, and Metabolic Outcomes, Volume 202 (Drugs and the Pharmaceutical Sciences)

Addressing the elevated use of protein and peptide applicants as remedies for formerly untreatable illnesses, this entire and innovative resource offers the reader with a roadmap to an elevated figuring out of matters severe for effectively constructing a protein or peptide healing candidate.

Ecstasy : The Complete Guide : A Comprehensive Look at the Risks and Benefits of MDMA

• The world's best specialists on Ecstasy determine its healing strength, social implications, and the hazards of unsupervised use. • contains chapters via Andrew Weil, Ralph Metzner, Douglas Rushkoff, Rabbi Zalman Schachter, Rick Doblin, and others. • a fantastic consultant for fogeys and educators looking a reputable resource of data.

Cannabis: a complete guide

Hashish sativa is healthier often called the resource of marijuana, the world’s most generally fed on illicit leisure drug. besides the fact that, the plant is additionally super invaluable as a resource of stem fiber, fit for human consumption seed oil, and medicinal compounds, all of that are present process super promising learn, technological purposes, and enterprise funding.

Additional resources for Carrier-Based Drug Delivery

Sample text

However, the pH required for destabilization was higher than the pH at which the polymer collapsed in solution in contrast to the case of the polymer-coated liposomes. ; ACS Symposium Series; American Chemical Society: Washington, DC, 2004. ch002 It is believed that hydrogen bonding with niosomes changed the pH of coil-toglobule transition of the copolymer, presumably by changing its hydration state. The strong interactions that occur between niosomes and the copolymer were expected to provide better anchoring of the polymer in bilayers and, consequently, greater stability of this system in biological fluids.

Macromol. 1998, 31, 5084-5093. 86. P. Stimuli-sensitive poly(methacrylic acid) microparticles (PMAA) - Oral insulin delivery. J. Biomater. Appl. 2002, 17, 125-134. 87. B. Chitosan micro­ -particle preparation for controlled drug release by response surface metho­ -dology. J. Microencapsulation 2003, 20, 791-797. 88. ;Langer, R. pH-triggered release of macromolecules from spray-dried polymethacrylatemicroparticles. Pharm. Res. 2003, 20, 1533-1538. 89. ; Labhasetwa, V. Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles.

Huang L. J. Biol. Chem. 1983, 258, 14034-14040. 4. H. Crit. Rev. Ther. Drug Carrier Syst. 1987, 3, 123-193. 5. ; Huang L. Biochim. Biophys. Acta 1990, 1025, 234-242. 6. C. FEBS Lett. 1998, 42, 61-64. 7. -C. Biochim. Biophys. Acta 2000, 1463, 383-394. 8. ; Principi T. ; ACS symposium series 780; American Chemical Society: Washington, DC. 2000 pp. 277-297. 9. -C. Biomacromolecules 2001, 2, 741-749. 10. ; Vanlerberghe G. Int. J. Cos. Sci. 1979, 1, 303-314. 11. A. Pharm. Weekb. 1988, 123, 355-363.

Download PDF sample

Rated 4.18 of 5 – based on 9 votes