By Edward D. Eanes (auth.), Antonio Pecile, Benedetto de Bernard (eds.)
From booklet information, Inc.
Includes all lectures offered on the NATO ASI direction held in Erice, Sicily, may perhaps 1989. Covers morphological, chemical, biochemical, physiological and pathophysiological features of bone formation and resorption, targeting regulatory components and indicating the recent instructions which are establishing up.
Annotation copyright ebook information, Inc. Portland, Or.
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K. Kleinman, Mineral and collagen-binding proteins of fetal calf bone, J. Biol. Chem. 256: 10403-10408 (1981). 113. P. Bianco, Y. Hayashi, G. O. Termine, and E. Bonucci, Osteonectin and GLA-protein in calf bone: ultrastructural immunohistochemical localization using the protein A-gold method, Calcif. Tiss. Int. 37: 684-686 (1984). 114. A. R. Urist, and Y. Otawara, Matrix Gla protein, a new -carboxyglutarnic acid-containing protein which is associated with the organic matrix of bone, Biochem. Biophys.
IJiuthier, Disposi tion of preformed minGral in matrix vesic1es. Internal localization and association with alkaline phosphatase, J. Biol. Chem. 262: 10481-10488 (1987). 38 MORPHOLOGICAL ANO QUANTITATIVE ASPECTS OF BONE FORMATION ANO MINERALIZATION Gastone Marotti Istituto di Anatomia umana normale, Universita di Modena Policlinica, Via Del Pozzo 71, Modena (Italy) 1NTRODUCTI ON Bone formation is a biphasic process. During the first phase, the osteoblasts secrete an organic matrix, called preosseous matrix or osteoid, made up of type I collagen and ground substance (proteoglycans, glycoproteins, non-collagenous proteins).
24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. T. Butler, A comparative immunocytochemical study on the subcellular distribution of 44kDa bone phosphoprotein and -carboxyglutamic acid (Gla)-containing protein in osteobone blasts. ~ Bone Min. Res. 2: 337-346 (1987). J. Bronckers, S. T. T. Butler, Immuno-carboxyglutamic acid-containing proteins in develocalization of loping molar tooth germs of the rat, Collag. Rel. Res. 5: 17-22 (1985). J. T. D. Finkelman, and A. Nanci Immunocyto-carboxyglutamic acid-containing protein chemical localization of (Osteocalcin) in rat bone and dentin, Calcif.