Atlas of Human Tumor Cell Lines by Robert K.M. Hay, Jae-Gahb Park, Adi Gazdar

By Robert K.M. Hay, Jae-Gahb Park, Adi Gazdar

Human tumor cells in tradition are beneficial for learning melanoma factors and houses. this useful reference presents precious details for melanoma researchers on general, verified tumor mobile strains of the key human organ systems.
Atlas of Human Tumor mobile Lines comprises information approximately morphological, metabolic, genetic, and development features of human tumor cells, with morphological features provided in additional than 250 photomicrographs. It additionally includes info for constructing and retaining human tumor cellphone traces in tradition, and every bankruptcy covers destiny views.

* Covers well-characterized tumor telephone strains from the main human organ systems
* provides over 250 photomicrographs, either phase-contrast and electron micrographs
* contains a checklist of key references for every chapter
* Written by way of world-renowned experts

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Tippets, R. , Thomas, G. , and White, R. (1989). Loss of heterozygosity for loci on chromosome 17p in human malignant astrocytoma. Cancer Res. 49, 6572-6577. , Pedone, C. , Thomas, G. , and White, R. (1990). Allelotype of human malignant astrocytoma. Cancer Res. 50, 5784-5789. , Tullous, M. , Pedone, C. , and Cawthon, R. M. (1992a). p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression. Cancer Res. 52, 674-679. , Pedone, C. , Morse, H. , Rose, J.

The classification of these tumors as a subgroup of PNETs was adopted (Rorke, 1983) because primitive neuroepithelial cells anywhere in the CNS are purported to be the targets of transformation, resulting in similar tumors, an event that seems to be most frequent in the cerebellum. Microscopically, medulloblastomas consist mainly of rounded or slightly elongated small cells with a high nucleus:cytoplasm ratio. , 1991). , 1990b). DMs have been found in some cases, which also had an amplified c-myc gene.

And Shapiro, W. R. (1985). The subpopulations and isolated cell types of freshly resected high-grade human gliomas: Their influence on the tumor's evolution in vivo and behavior and therapy in vitro. Cancer Metab. Rev. 4, 107-124. Shapiro, J. -K. , and Shapiro, W. R. (1981). Isolation, karyotype and clonal growth of heterogeneous subpopulations of human malignant gliomas. Cancer Res. 41, 2349-2359. , Rodgers, L, and Wigler, M. (1989). Characterization of the rosl-gene products expressed in human glioblastoma cell lines.

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