Artemisia annua - Pharmacology and Biotechnology by Elisabeth Hsu (auth.), Tariq Aftab, Jorge F.S. Ferreira, M.

By Elisabeth Hsu (auth.), Tariq Aftab, Jorge F.S. Ferreira, M. Masroor A. Khan, M. Naeem (eds.)

Artemisinin, a sesquiterpene lactone initially extracted from the medicinal plant Artemisia annua L., is an efficient antimalarial agent, quite for multi-drug resistant and cerebral malaria. despite the fact that, the focus of artemisinin within the plant is especially low. as the chemical synthesis of artemisinin is advanced and never economically possible in view of the terrible yield of the drug, the intact plant is still the one manageable resource of artemisinin construction. hence, it can be crucial to extend the focus of artemisinin in A. annua to minimize the price of artemisinin dependent antimalarial medicinal drugs. Plant scientists have centred their efforts on A. annua for a better artemisinin crop yield. With the current quantity, we're bringing jointly the study that is being performed in this plant through the global and destiny probabilities for scientists and researchers who are looking to paintings on it.

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They reported parasite clearance times and fever clearance times were significantly faster for all the herbal preparations than for chloroquine. Patients were followed up for 30 days, with a blood film examined for parasitemia every 10 days. About one in three patients who had taken the capsules for 3 days only experienced a recrudescence, but this was reduced to only 8 % in those who had taken the capsules for 6 days. The larger clinical trials of different A. 2 (Wilcox et al. 2004a, b). Mueller et al.

Planta Med 69:1–11 Aftab T, Khan MMA, Idrees M, da Silva JAT, Naeem M et al (2012) Exogenous nitric oxide protects Artemisia annua from oxidative stress generated by boron and aluminium toxicity. Ecotoxicol Environ Safe 80:60–68 Aftab T, Khan MMA, Idrees M, Naeem M, Hashmi N et al (2010a) Effect of salt stress on growth, membrane damage, antioxidant metabolism and artemisinin accumulation in Artemisia annua L. Plant Stress 4:36–43 Aftab T, Khan MMA, Idrees M, Naeem M, Ram M (2010b) Boron induced oxidative stress, antioxidant defense response and changes in artemisinin content in Artemisia annua L.

Initially clear but then reappear as late as day 42). A meta-analysis of clinical trials on 1919 patients has shown that artemether is at least as effective as quinine and is associated with fewer serious adverse effects (Artemether–Quinine Meta-analysis study group 2001). Chang and But (1986) reported that dilute alcohol extract of the herb, given as a total dose of 72 g of crude extract over 3 days in divided doses. The cure rate was said to be 100 % in 485 cases of P. vivax and 105 cases of P.

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