Antisepsis, Disinfection, and Sterilization: Types, Action, by Gerald E. McDonnell

By Gerald E. McDonnell

This new identify presents a easy knowing of many of the chemical and actual antisepsis, disinfection, and sterlization tools used for an infection prevention and illness keep an eye on. It considers the present realizing of mechanisms of biocidal motion on microorganisms and describes the less-studied mechanisms of resistance in viruses, prions, fungi, and different eukaryotes. offers a entire evaluate of many of the chemical and actual antisepsis, disinfection, and sterilization tools bargains historical past details on microbiology, together with a dialogue of the spectrum of motion, choice of efficacy, and customary variables that impact the functionality of antisepsis, disinfection, and sterilization tools covers the mechanisms of motion of biocides in 4 basic teams: oxidizing brokers, cross-linking brokers, motion by way of move of power, and different structure-disrupting brokers explores the established common and bought mechanisms microorganisms hire to withstand the biocidal results of chemical and actual procedures

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Additional info for Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance

Example text

For example, a sterilizing agent is expected to be effective against viruses, fungi, protozoa, mycobacteria, and other bacteria, including bacterial spores. Bacteria (including spores), fungi, mycobacteria, and to a lesser extent viruses are most commonly used as test microorganisms. 17). Despite acceptance of these surrogates, in some cases the specific test organisms are used, or are required to be used, to verify the claimed antimicrobial activity. These tests not only are important in the investigation of biocides and the development of products and processes but are also the basis for the regulatory clearance, labeling, and use of antiseptics, disinfectants, and sterilization processes.

Similar to foot-and-mouth disease; flu-like Coronaviridae (RNA, enveloped) Human coronavirus . . . . . . . . . . . . . . . . . . . Severe acute respiratory syndrome, colds Mouse hepatitis virus . . . . . . . . . . . . . . . . . . Wasting syndrome Herpesviridae (DNA, enveloped) Herpesvirus (herpes simplex virus types 1 and 2) . . . . . . . Conjunctivitis, gingivostomatitis, genital herpes, meningitis Varicella-zoster virus . . . .

Pyogenes and S. pneumoniae are both associated with upper and lower respiratory tract diseases, including pharyngitis (sore throat), pneumonia, and scarlet fever. S. , cellulitis). G. stearothermophilus spores are widely regarded as the most resistant to heat and other sterilization methods; used as biological indicators of sterilization efficacy. , B. atrophaeus, formally known as B. subtilis, for ethylene oxide sterilization); some strains also pathogenic, including B. cereus (food poisoning) and B.

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